Autoimmune Defense and Living Environment

The ADELE ecosystem project studies environmental factors that are associated with the development of immune-mediated diseases. The ecosystem also develops proof of concept materials, prototypes and ways to prevent the development of immune-mediated diseases. Such diseases include most allergies, asthma, rheumatoid arthritis, type 1 diabetes, Crohn's disease and ulcerative colitis. An important common denominator of these diseases is limited microbial exposure, whereas repeated exposure to environmental microbial diversity has been considered as a key in protecting against these diseases. In this context, environmental microbial diversity means exposure to a diverse microbial community in forests and meadows. Today, environmental microbial diversity must be received by going out into nature, which is difficult if not impossible in urban areas. The ADELE ecosystem targets to consumer products that include added biodiversity component. These products support the normal development of immune system and protect against immune-mediated diseases.


Jun.-Prof. Dr.-Ing. Martin Knöll
Raul Kalvo

In cooperation with

University of Helsinki
University of Tampere
Tampere University of Technology
+ 7 Finnish companies


The project runs from 04/2018 – 03/2021.


Total budget of the project for three years is about 3.1 million euros. Main funding body: Business Finland